Gene description for Pgk
Gene name Phosphoglycerate kinase
Gene symbol Pgk
Other names/aliases 169C9S
CG3127
DmelCG3127
ESTS:169C9S
PGK
anon-sts18
l(2)23AB3
l(2)23Ac
pgk
Species Drosophila melanogaster
 Database cross references - Pgk
ExoCarta ExoCarta_33461
Entrez Gene 33461
UniProt Q01604  
 Pgk identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Pgk
Molecular Function
    ATP binding GO:0005524 ISS
    phosphoglycerate kinase activity GO:0004618 NAS
Biological Process
    myoblast fusion GO:0007520 IMP
    somatic muscle development GO:0007525 IMP
    phosphorylation GO:0016310 ISS
    muscle cell cellular homeostasis GO:0046716 IGI
    synaptic transmission GO:0007268 IDA
    glycolytic process GO:0006096 NAS
Subcellular Localization
    Z disc GO:0030018 IDA
    cytoplasm GO:0005737 NAS
    M band GO:0031430 IDA
 Experiment description of studies that identified Pgk in exosomes
1
Experiment ID 202
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG10|RAB35
EV Cytosolic markers
✔
FLOT2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pgk
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pgk is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Glycolysis IEA Reactome





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