Gene description for HINT1
Gene name histidine triad nucleotide binding protein 1
Gene symbol HINT1
Other names/aliases -
Species Bos taurus
 Database cross references - HINT1
ExoCarta ExoCarta_327693
Entrez Gene 327693
UniProt P62958  
 HINT1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HINT1
Molecular Function
    hydrolase activity GO:0016787 ISS
    nucleotide binding GO:0000166 IEA
Biological Process
    intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 ISS
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 ISS
    purine ribonucleotide catabolic process GO:0009154 ISS
Subcellular Localization
    histone deacetylase complex GO:0000118 ISS
    extracellular exosome GO:0070062 IEA
    plasma membrane GO:0005886 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified HINT1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HINT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HINT1 is involved
No pathways found





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