Gene description for Pisd
Gene name phosphatidylserine decarboxylase
Gene symbol Pisd
Other names/aliases 9030221M09Rik
Species Mus musculus
 Database cross references - Pisd
ExoCarta ExoCarta_320951
Vesiclepedia VP_320951
Entrez Gene 320951
UniProt Q8BSF4  
 Pisd identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pisd
Molecular Function
    phosphatidylserine decarboxylase activity GO:0004609 IBA
    phosphatidylserine decarboxylase activity GO:0004609 ISO
    phosphatidylserine decarboxylase activity GO:0004609 ISS
Biological Process
    phosphatidylethanolamine biosynthetic process GO:0006646 IBA
    phosphatidylethanolamine biosynthetic process GO:0006646 IEA
    phosphatidylethanolamine biosynthetic process GO:0006646 ISO
    phosphatidylethanolamine biosynthetic process GO:0006646 ISS
    regulation of mitochondrion organization GO:0010821 ISO
    regulation of mitochondrion organization GO:0010821 ISS
    protein autoprocessing GO:0016540 IEA
    mitochondrial protein catabolic process GO:0035694 ISO
    mitochondrial protein catabolic process GO:0035694 ISS
    lipid droplet formation GO:0140042 ISO
    lipid droplet formation GO:0140042 ISS
Subcellular Localization
    nucleus GO:0005634 ISO
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 IEA
    Golgi apparatus GO:0005794 ISO
    lipid droplet GO:0005811 ISO
    lipid droplet GO:0005811 ISS
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Pisd in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pisd
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pisd is involved
No pathways found





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