Gene description for Phf8
Gene name	PHD finger protein 8
Gene symbol	Phf8
Other names/aliases	9830141C09Rik mKIAA1111
Species	Mus musculus
Database cross references - Phf8
ExoCarta	ExoCarta_320595
Vesiclepedia	VP_320595
Entrez Gene	320595
UniProt	Q80TJ7
Phf8 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Phf8

Molecular Function     chromatin binding GO:0003682 ISO     chromatin binding GO:0003682 ISS     transcription coregulator activity GO:0003712 IBA     iron ion binding GO:0005506 ISO     iron ion binding GO:0005506 ISS     zinc ion binding GO:0008270 ISO     zinc ion binding GO:0008270 ISS     2-oxoglutarate-dependent dioxygenase activity GO:0016706 ISO     2-oxoglutarate-dependent dioxygenase activity GO:0016706 ISS     histone demethylase activity GO:0032452 IBA     histone demethylase activity GO:0032452 ISO     histone demethylase activity GO:0032452 ISS     histone H3K9 demethylase activity GO:0032454 ISO     histone H3K9 demethylase activity GO:0032454 ISS     methylated histone binding GO:0035064 ISO     methylated histone binding GO:0035064 ISS     histone H4K20 demethylase activity GO:0035575 ISO     histone H4K20 demethylase activity GO:0035575 ISS     histone H3K36 demethylase activity GO:0051864 ISO     histone H3K36 demethylase activity GO:0051864 ISS     histone H3K27me2/H3K27me3 demethylase activity GO:0071558 ISO     histone H3K27me2/H3K27me3 demethylase activity GO:0071558 ISS     histone H3K36me/H3K36me2 demethylase activity GO:0140680 IEA     histone H3K9me/H3K9me2 demethylase activity GO:0140683 IEA     FAD-dependent histone H3K9me/H3K9me2 demethylase activity GO:0140685 IEA Biological Process     G1/S transition of mitotic cell cycle GO:0000082 ISO     G1/S transition of mitotic cell cycle GO:0000082 ISS     chromatin remodeling GO:0006338 IBA     chromatin remodeling GO:0006338 IEA     regulation of transcription by RNA polymerase II GO:0006357 IBA     brain development GO:0007420 ISS     positive regulation of DNA-templated transcription GO:0045893 ISO     positive regulation of DNA-templated transcription GO:0045893 ISS     positive regulation of transcription by RNA polymerase I GO:0045943 ISO     positive regulation of transcription by RNA polymerase I GO:0045943 ISS     positive regulation of transcription by RNA polymerase II GO:0045944 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     negative regulation of rDNA heterochromatin formation GO:0061188 ISO     negative regulation of rDNA heterochromatin formation GO:0061188 ISS Subcellular Localization     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     nucleolus GO:0005730 ISO     nucleolus GO:0005730 ISS     nuclear membrane GO:0031965 IEA     nuclear membrane GO:0031965 ISO