Gene description for Rfx7
Gene name regulatory factor X, 7
Gene symbol Rfx7
Other names/aliases 2510005N23Rik
9930116O05Rik
D130086K05Rik
Rfxdc2
Species Mus musculus
 Database cross references - Rfx7
ExoCarta ExoCarta_319758
Vesiclepedia VP_319758
Entrez Gene 319758
 Rfx7 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rfx7
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    RNA polymerase II core promoter sequence-specific DNA binding GO:0000979 IDA
    RNA polymerase II core promoter sequence-specific DNA binding GO:0000979 ISO
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    DNA-binding transcription factor activity GO:0003700 IEA
    sequence-specific double-stranded DNA binding GO:1990837 ISO
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    positive regulation of DNA-templated transcription GO:0045893 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IEA
    positive regulation of transcription by RNA polymerase II GO:0045944 ISO
Subcellular Localization
    nucleus GO:0005634 IDA
 Experiment description of studies that identified Rfx7 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rfx7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rfx7 is involved
No pathways found





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