Gene description for Idi1
Gene name isopentenyl-diphosphate delta isomerase
Gene symbol Idi1
Other names/aliases 4832416K17Rik
Species Mus musculus
 Database cross references - Idi1
ExoCarta ExoCarta_319554
Vesiclepedia VP_319554
Entrez Gene 319554
UniProt P58044  
 Idi1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Idi1
Molecular Function
    magnesium ion binding GO:0000287 ISO
    isopentenyl-diphosphate delta-isomerase activity GO:0004452 IBA
    isopentenyl-diphosphate delta-isomerase activity GO:0004452 IEA
    isopentenyl-diphosphate delta-isomerase activity GO:0004452 ISO
    manganese ion binding GO:0030145 ISO
    metal ion binding GO:0046872 IEA
Biological Process
    cholesterol biosynthetic process GO:0006695 IEA
    isoprenoid biosynthetic process GO:0008299 IEA
    isoprenoid biosynthetic process GO:0008299 ISO
    isopentenyl diphosphate biosynthetic process GO:0009240 IBA
    response to stilbenoid GO:0035634 IEP
    dimethylallyl diphosphate biosynthetic process GO:0050992 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    mitochondrion GO:0005739 HDA
    peroxisome GO:0005777 ISO
 Experiment description of studies that identified Idi1 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Idi1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kcnma1  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Idi1 is involved
PathwayEvidenceSource
Cholesterol biosynthesis IEA Reactome
Metabolism IEA Reactome
Metabolism of lipids IEA Reactome
Metabolism of steroids IEA Reactome





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