Gene description for Fem1a
Gene name	fem-1 homolog a (C. elegans)
Gene symbol	Fem1a
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Fem1a
ExoCarta	ExoCarta_316131
Vesiclepedia	VP_316131
Entrez Gene	316131
UniProt	Q4V890
Fem1a identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells	20124479
Pancreatic cancer cells	20124479

Gene ontology annotations for Fem1a

Molecular Function     EP4 subtype prostaglandin E2 receptor binding GO:0031867 ISO     molecular adaptor activity GO:0060090 ISO     ubiquitin-like ligase-substrate adaptor activity GO:1990756 IBA     ubiquitin-like ligase-substrate adaptor activity GO:1990756 ISO     ubiquitin-like ligase-substrate adaptor activity GO:1990756 ISS Biological Process     protein ubiquitination GO:0016567 IEA     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IBA     negative regulation of MAP kinase activity GO:0043407 ISO     negative regulation of inflammatory response GO:0050728 IBA     negative regulation of inflammatory response GO:0050728 ISO     negative regulation of inflammatory response GO:0050728 ISO     positive regulation of inflammatory response GO:0050729 ISO     positive regulation of inflammatory response GO:0050729 ISS     regulation of ubiquitin-protein transferase activity GO:0051438 ISS     ubiquitin-dependent protein catabolic process via the C-end degron rule pathway GO:0140627 ISO     ubiquitin-dependent protein catabolic process via the C-end degron rule pathway GO:0140627 ISS Subcellular Localization     ubiquitin ligase complex GO:0000151 IBA     cytoplasm GO:0005737 ISO     mitochondrion GO:0005739 ISO     mitochondrion GO:0005739 ISO     mitochondrion GO:0005739 ISS     Cul2-RING ubiquitin ligase complex GO:0031462 ISO     Cul2-RING ubiquitin ligase complex GO:0031462 ISS