Gene description for Krt4
Gene name keratin 4, type II
Gene symbol Krt4
Other names/aliases Kb4
Species Rattus norvegicus
 Database cross references - Krt4
ExoCarta ExoCarta_315323
Entrez Gene 315323
UniProt Q6IG00  
 Krt4 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Krt4
Molecular Function
    molecular_function GO:0003674 ND
    structural molecule activity GO:0005198 IEA
Biological Process
    negative regulation of epithelial cell proliferation GO:0050680 ISS
    cytoskeleton organization GO:0007010 ISO
    biological_process GO:0008150 ND
    epithelial cell differentiation GO:0030855 ISS
Subcellular Localization
    cell surface GO:0009986 ISO
    nucleus GO:0005634 ISO
    intermediate filament cytoskeleton GO:0045111 ISO
    cellular_component GO:0005575 ND
    keratin filament GO:0045095 ISO
 Experiment description of studies that identified Krt4 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Krt4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Krt4 is involved
No pathways found





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