Gene description for Akr1c19
Gene name aldo-keto reductase family 1, member C19
Gene symbol Akr1c19
Other names/aliases RGD1562954
Species Rattus norvegicus
 Database cross references - Akr1c19
ExoCarta ExoCarta_307096
Vesiclepedia VP_307096
Entrez Gene 307096
 Akr1c19 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Akr1c19
Molecular Function
    aldose reductase (NADPH) activity GO:0004032 IBA
    bile acid binding GO:0032052 IBA
    androsterone dehydrogenase activity GO:0047023 IBA
    ketosteroid monooxygenase activity GO:0047086 IBA
Biological Process
    prostaglandin metabolic process GO:0006693 IBA
    progesterone metabolic process GO:0042448 IBA
    daunorubicin metabolic process GO:0044597 IBA
    doxorubicin metabolic process GO:0044598 IBA
Subcellular Localization
    cytosol GO:0005829 IBA
 Experiment description of studies that identified Akr1c19 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Akr1c19
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Akr1c19 is involved
No pathways found





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