Gene description for Lamp3
Gene name lysosomal-associated membrane protein 3
Gene symbol Lamp3
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Lamp3
ExoCarta ExoCarta_303801
Vesiclepedia VP_303801
Entrez Gene 303801
UniProt Q5XI99  
 Lamp3 identified in sEVs derived from the following tissue/cell type
Dendritic cells 19812188    
 Gene ontology annotations for Lamp3
Biological Process
    adaptive immune response GO:0002250 IEA
    regulation of autophagy GO:0010506 ISO
    positive regulation of gene expression GO:0010628 ISO
    response to interferon-alpha GO:0035455 ISO
    establishment of protein localization to organelle GO:0072594 IBA
    negative regulation of proteasomal protein catabolic process GO:1901799 ISO
    regulation of viral life cycle GO:1903900 ISO
Subcellular Localization
    lysosomal membrane GO:0005765 IBA
    lysosomal membrane GO:0005765 IEA
    lysosomal membrane GO:0005765 ISO
    early endosome GO:0005769 ISO
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISO
    cell surface GO:0009986 IEA
    endosome membrane GO:0010008 IEA
    early endosome membrane GO:0031901 IEA
    late endosome membrane GO:0031902 IBA
    vesicle GO:0031982 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    perinuclear region of cytoplasm GO:0048471 ISO
    alveolar lamellar body membrane GO:0097233 IDA
    alveolar lamellar body membrane GO:0097233 ISO
 Experiment description of studies that identified Lamp3 in sEVs
1
Experiment ID 69
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19812188    
Organism Rattus norvegicus
Experiment description Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII.
Authors "Miksa M, Wu R, Dong W, Komura H, Amin D, Ji Y, Wang Z, Wang H, Ravikumar TS, Tracey KJ, Wang P"
Journal name JIMMU
Publication year 2009
Sample Dendritic cells
Sample name Bone marrow-derived immature dendritic cells
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
 Protein-protein interactions for Lamp3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lamp3 is involved
No pathways found





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