|
Gene description for NPC1L1 |
| Gene name |
NPC1-like 1 |
| Gene symbol |
NPC1L1 |
| Other names/aliases |
NPC11L1 |
| Species |
Homo sapiens |
Database cross references - NPC1L1 |
| ExoCarta |
ExoCarta_29881 |
| Vesiclepedia |
VP_29881 |
| Entrez Gene |
29881 |
| HGNC |
7898 |
| MIM |
608010 |
| UniProt |
Q9UHC9
|
NPC1L1 identified in sEVs derived from the following tissue/cell type |
|
Pancreatic duct fluid
|
29339034
|
|
Pancreatic duct fluid
|
29339034
|
Gene ontology annotations for NPC1L1 |
|
|
Experiment description of studies that identified NPC1L1 in sEVs |
| 1 |
| Experiment ID |
622 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
|
Enriched markers |
|
✔
GOLGA2|CYC1
|
Negative markers |
|
✔
NTA
|
Particle analysis
|
|
| Identified molecule |
Protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
29339034
|
| Organism |
Homo sapiens |
| Experiment description |
Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer |
| Authors |
"Zheng J, Hernandez JM, Doussot A, Bojmar L, Zambirinis CP, Costa-Silva B, van Beek EJAH, Mark MT, Molina H, Askan G, Basturk O, Gonen M, Kingham TP, Allen PJ, D'Angelica MI, DeMatteo RP, Lyden D, Jarnagin WR." |
| Journal name |
HPB
|
| Publication year |
2018 |
| Sample |
Pancreatic duct fluid |
| Sample name |
From patients with Pancreatic ductal adenocarcinoma |
| Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 2 |
| Experiment ID |
623 |
| MISEV standards |
|
✘
|
Biophysical techniques |
|
|
Enriched markers |
|
✔
GOLGA2|CYC1
|
Negative markers |
|
✔
NTA
|
Particle analysis
|
|
| Identified molecule |
Protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
29339034
|
| Organism |
Homo sapiens |
| Experiment description |
Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer |
| Authors |
"Zheng J, Hernandez JM, Doussot A, Bojmar L, Zambirinis CP, Costa-Silva B, van Beek EJAH, Mark MT, Molina H, Askan G, Basturk O, Gonen M, Kingham TP, Allen PJ, D'Angelica MI, DeMatteo RP, Lyden D, Jarnagin WR." |
| Journal name |
HPB
|
| Publication year |
2018 |
| Sample |
Pancreatic duct fluid |
| Sample name |
From patients with IPMN with microinvasive cancer (IPMNca) |
| Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
Protein-protein interactions for NPC1L1 |
|
|
Pathways in which NPC1L1 is involved |
|
|
|