Gene description for Ccl20
Gene name chemokine (C-C motif) ligand 20
Gene symbol Ccl20
Other names/aliases ST38
Scya20
Species Rattus norvegicus
 Database cross references - Ccl20
ExoCarta ExoCarta_29538
Vesiclepedia VP_29538
Entrez Gene 29538
UniProt P97884  
 Ccl20 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Ccl20
Molecular Function
    cytokine activity GO:0005125 ISO
    chemokine activity GO:0008009 IDA
    chemokine activity GO:0008009 IEA
    CCR6 chemokine receptor binding GO:0031731 ISO
    CCR6 chemokine receptor binding GO:0031731 ISS
Biological Process
    regulation of T cell cytokine production GO:0002724 ISO
    chemotaxis GO:0006935 IDA
    chemotaxis GO:0006935 ISO
    inflammatory response GO:0006954 IEA
    immune response GO:0006955 IEA
    signal transduction GO:0007165 IEA
    calcium-mediated signaling GO:0019722 ISO
    calcium-mediated signaling GO:0019722 ISS
    positive regulation of interleukin-1 alpha production GO:0032730 IDA
    cell chemotaxis GO:0060326 IEA
    cell chemotaxis GO:0060326 ISO
    antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 ISO
    cellular response to lipopolysaccharide GO:0071222 IEP
    cellular response to lipoteichoic acid GO:0071223 IEP
    T cell migration GO:0072678 ISO
    T cell migration GO:0072678 ISS
    thymocyte migration GO:0072679 ISO
    thymocyte migration GO:0072679 ISS
    regulation of T-helper 17 cell differentiation GO:2000319 ISO
    positive regulation of T cell migration GO:2000406 ISO
Subcellular Localization
    extracellular space GO:0005615 IDA
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified Ccl20 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Ccl20
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here