Gene description for Pepd
Gene name peptidase D
Gene symbol Pepd
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Pepd
ExoCarta ExoCarta_292808
Vesiclepedia VP_292808
Entrez Gene 292808
UniProt Q5I0D7  
 Pepd identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Pepd
Molecular Function
    peptidase activity GO:0008233 IBA
    peptidase activity GO:0008233 ISO
    manganese ion binding GO:0030145 IEA
    metalloaminopeptidase activity GO:0070006 IEA
    proline dipeptidase activity GO:0102009 IEA
    proline dipeptidase activity GO:0102009 ISO
    proline dipeptidase activity GO:0102009 ISS
Biological Process
    proteolysis GO:0006508 IBA
    proteolysis GO:0006508 IEA
    proteolysis GO:0006508 ISO
    proteolysis GO:0006508 ISS
    collagen catabolic process GO:0030574 IEA
    negative regulation of programmed cell death GO:0043069 IEA
    negative regulation of programmed cell death GO:0043069 ISO
    negative regulation of programmed cell death GO:0043069 ISS
 Experiment description of studies that identified Pepd in sEVs
1
Experiment ID 95
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Pepd
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pepd is involved
No pathways found





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