Gene description for Stx11
Gene name syntaxin 11
Gene symbol Stx11
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Stx11
ExoCarta ExoCarta_292483
Vesiclepedia VP_292483
Entrez Gene 292483
 Stx11 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Stx11
Molecular Function
    SNARE binding GO:0000149 IBA
    SNAP receptor activity GO:0005484 IBA
Biological Process
    T cell mediated cytotoxicity GO:0001913 ISO
    intracellular protein transport GO:0006886 IBA
    exocytosis GO:0006887 IBA
    synaptic vesicle fusion to presynaptic active zone membrane GO:0031629 IBA
    natural killer cell mediated cytotoxicity GO:0042267 ISO
    neutrophil degranulation GO:0043312 ISO
    cytotoxic T cell degranulation GO:0043316 ISO
    natural killer cell degranulation GO:0043320 ISO
    vesicle docking GO:0048278 IBA
    cellular response to type II interferon GO:0071346 ISO
Subcellular Localization
    plasma membrane GO:0005886 IBA
    endomembrane system GO:0012505 IBA
    SNARE complex GO:0031201 IBA
    phagocytic vesicle GO:0045335 ISO
    presynaptic active zone membrane GO:0048787 IBA
 Experiment description of studies that identified Stx11 in sEVs
1
Experiment ID 97
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Stx11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Stx11 is involved
No pathways found





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