Gene description for Aldh7a1
Gene name aldehyde dehydrogenase 7 family, member A1
Gene symbol Aldh7a1
Other names/aliases antiquitin
Species Rattus norvegicus
 Database cross references - Aldh7a1
ExoCarta ExoCarta_291450
Vesiclepedia VP_291450
Entrez Gene 291450
UniProt Q64057  
 Aldh7a1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Aldh7a1
Molecular Function
    aldehyde dehydrogenase (NAD+) activity GO:0004029 IEA
    aldehyde dehydrogenase (NAD+) activity GO:0004029 ISO
    aldehyde dehydrogenase (NAD+) activity GO:0004029 ISS
    L-aminoadipate-semialdehyde dehydrogenase activity GO:0004043 IEA
    betaine-aldehyde dehydrogenase (NAD+) activity GO:0008802 IEA
    betaine-aldehyde dehydrogenase (NAD+) activity GO:0008802 ISO
    betaine-aldehyde dehydrogenase (NAD+) activity GO:0008802 ISS
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    identical protein binding GO:0042802 ISS
Biological Process
    glycine betaine biosynthetic process from choline GO:0019285 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    mitochondrion GO:0005739 IEA
    mitochondrion GO:0005739 ISO
    mitochondrion GO:0005739 ISS
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    cytosol GO:0005829 ISS
 Experiment description of studies that identified Aldh7a1 in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Aldh7a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aldh7a1 is involved
PathwayEvidenceSource
Choline catabolism IEA Reactome
Lysine catabolism IEA Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome





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