Gene description for Cope
Gene name coatomer protein complex, subunit epsilon
Gene symbol Cope
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Cope
ExoCarta ExoCarta_290659
Vesiclepedia VP_290659
Entrez Gene 290659
 Cope identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Cope
Molecular Function
    structural molecule activity GO:0005198 IEA
Biological Process
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 IBA
    retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890 IEA
    intra-Golgi vesicle-mediated transport GO:0006891 IBA
    protein transport GO:0015031 IEA
    protein localization to axon GO:0099612 ISO
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    Golgi apparatus GO:0005794 ISO
    COPI vesicle coat GO:0030126 IBA
    COPI-coated vesicle GO:0030137 ISO
 Experiment description of studies that identified Cope in sEVs
1
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Cope
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 STXBP5L  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Cope is involved
No pathways found





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