Gene description for Psme3
Gene name proteasome (prosome, macropain) activator subunit 3
Gene symbol Psme3
Other names/aliases Ab2-371
Species Rattus norvegicus
 Database cross references - Psme3
ExoCarta ExoCarta_287716
Entrez Gene 287716
 Psme3 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Psme3
Molecular Function
    p53 binding GO:0002039 IEA
    peptidase activity GO:0008233 IEA
    endopeptidase activator activity GO:0061133 IEA
    MDM2/MDM4 family protein binding GO:0097371 IEA
Biological Process
    proteolysis GO:0006508 IEA
    positive regulation of endopeptidase activity GO:0010950 IEA
    regulation of proteasomal protein catabolic process GO:0061136 IEA
    negative regulation of extrinsic apoptotic signaling pathway GO:2001237 IEA
Subcellular Localization
    proteasome activator complex GO:0008537 IEA
    cytoplasm GO:0005737 IEA
    membrane GO:0016020 IEA
    nucleoplasm GO:0005654 IEA
 Experiment description of studies that identified Psme3 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Psme3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Psme3 is involved
No pathways found





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