|
 Gene description for Cyp2d5 |
| Gene name |
cytochrome P450, family 2, subfamily d, polypeptide 5 |
| Gene symbol |
Cyp2d5 |
| Other names/aliases |
Cyp2d10 |
| Species |
Rattus norvegicus |
| Database cross references - Cyp2d5 |
| ExoCarta |
ExoCarta_286963 |
| Vesiclepedia |
VP_286963 |
| Entrez Gene |
286963 |
| UniProt |
P12939
|
| Cyp2d5 identified in sEVs derived from the following tissue/cell type |
|
Hepatocytes
|
19367702
|
| Gene ontology annotations for Cyp2d5 |
| Molecular Function |
| |
monooxygenase activity |
GO:0004497 |
IEA |
|
| |
monooxygenase activity |
GO:0004497 |
TAS |
|
| |
iron ion binding |
GO:0005506 |
IEA |
|
| |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
GO:0016705 |
IEA |
|
| |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
GO:0016712 |
IBA |
|
| |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
GO:0016712 |
IEA |
|
| |
heme binding |
GO:0020037 |
IBA |
|
| |
heme binding |
GO:0020037 |
IEA |
|
| Biological Process |
| |
xenobiotic metabolic process |
GO:0006805 |
IBA |
|
| |
arachidonate metabolic process |
GO:0019369 |
IBA |
|
| Subcellular Localization |
| |
cytoplasm |
GO:0005737 |
IBA |
|
| |
endoplasmic reticulum membrane |
GO:0005789 |
IEA |
|
| |
intracellular membrane-bounded organelle |
GO:0043231 |
IBA |
|
|
| Experiment description of studies that identified Cyp2d5 in sEVs |
| 1 |
| Experiment ID |
35 |
| MISEV standards |
|
✔
CEM
|
Biophysical techniques |
|
✔
TSG101|Alix|CD81|CD63
|
Enriched markers |
|
✔
HSPA5
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
19367702
|
| Organism |
Rattus norvegicus |
| Experiment description |
Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. |
| Authors |
"Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM" |
| Journal name |
JPR
|
| Publication year |
2008 |
| Sample |
Hepatocytes |
| Sample name |
Hepatocytes |
| Isolation/purification methods |
Differential centrifugation
Filtration
Sucrose density gradient |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [QTOF]
Western blotting |
|
|
| Protein-protein interactions for Cyp2d5 |
| |
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
|
No interactions are found.
|
|
| Pathways in which Cyp2d5 is involved |
|
No pathways found
|
|
|
