Gene description for Ugt2b1
Gene name UDP glucuronosyltransferase 2 family, polypeptide B1
Gene symbol Ugt2b1
Other names/aliases 2B1
Udpgtr2
Ugt2b17
Species Rattus norvegicus
 Database cross references - Ugt2b1
ExoCarta ExoCarta_286954
Vesiclepedia VP_286954
Entrez Gene 286954
UniProt P09875  
 Ugt2b1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Ugt2b1
Molecular Function
    retinoic acid binding GO:0001972 ISO
    UDP-glycosyltransferase activity GO:0008194 IEA
    glucuronosyltransferase activity GO:0015020 IBA
    glucuronosyltransferase activity GO:0015020 IDA
    glucuronosyltransferase activity GO:0015020 IMP
    glucuronosyltransferase activity GO:0015020 ISO
Biological Process
    xenobiotic metabolic process GO:0006805 TAS
    estrogen metabolic process GO:0008210 IDA
    estrogen metabolic process GO:0008210 ISO
    protein glucuronidation GO:0018411 IDA
    protein O-glucuronidation GO:0018412 IDA
    response to lipopolysaccharide GO:0032496 IEP
    cellular glucuronidation GO:0052695 IDA
    cellular glucuronidation GO:0052695 ISO
    biphenyl catabolic process GO:0070980 IDA
    cellular response to ethanol GO:0071361 IEP
    cellular response to growth hormone stimulus GO:0071378 IEP
    cellular response to glucocorticoid stimulus GO:0071385 IEP
    cellular response to testosterone stimulus GO:0071394 IEP
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified Ugt2b1 in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Ugt2b1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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