|
Gene description for PRR18 |
| Gene name |
proline rich 18 |
| Gene symbol |
PRR18 |
| Other names/aliases |
- |
| Species |
Homo sapiens |
Database cross references - PRR18 |
| ExoCarta |
ExoCarta_285800 |
| Vesiclepedia |
VP_285800 |
| Entrez Gene |
285800 |
| HGNC |
28574 |
| UniProt |
Q8N4B5
|
PRR18 identified in sEVs derived from the following tissue/cell type |
|
Hepatocellular carcinoma cells
|
26054723
|
|
Hepatocytes
|
26054723
|
Gene ontology annotations for PRR18 |
|
|
Experiment description of studies that identified PRR18 in sEVs |
| 1 |
| Experiment ID |
235 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
TSG101|Alix|HSC70|GAPDH
|
Enriched markers |
|
✔
HSP90B1
|
Negative markers |
|
✔
qNano
|
Particle analysis
|
|
| Identified molecule |
mRNA
|
| Identification method |
RNA Sequencing
|
| PubMed ID |
26054723
|
| Organism |
Homo sapiens |
| Experiment description |
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs |
| Authors |
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" |
| Journal name |
Carcinogenesis
|
| Publication year |
2015 |
| Sample |
Hepatocellular carcinoma cells |
| Sample name |
HKCI-8 |
| Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient |
| Flotation density |
1.13-1.19 g/mL
|
| Molecules identified in the study |
Protein RNA |
| Methods used in the study |
Western blotting Mass spectrometry RT-PCR RNA Sequencing |
|
|
| 2 |
| Experiment ID |
237 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
TSG101|Alix|HSC70|GAPDH
|
Enriched markers |
|
✔
HSP90B1
|
Negative markers |
|
✔
qNano
|
Particle analysis
|
|
| Identified molecule |
mRNA
|
| Identification method |
RNA Sequencing
|
| PubMed ID |
26054723
|
| Organism |
Homo sapiens |
| Experiment description |
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs |
| Authors |
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" |
| Journal name |
Carcinogenesis
|
| Publication year |
2015 |
| Sample |
Hepatocytes |
| Sample name |
MIHA |
| Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient |
| Flotation density |
1.13-1.19 g/mL
|
| Molecules identified in the study |
Protein RNA |
| Methods used in the study |
Western blotting Mass spectrometry RNA Sequencing |
|
|
Protein-protein interactions for PRR18 |
| |
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
|
No interactions are found.
|
|
Pathways in which PRR18 is involved |
|
No pathways found
|
|
|