Gene description for S100A12
Gene name S100 calcium binding protein A12
Gene symbol S100A12
Other names/aliases CAAF1
CAGC
CO-AG
EN-RAGE
Species Bos taurus
 Database cross references - S100A12
ExoCarta ExoCarta_282467
Vesiclepedia VP_282467
Entrez Gene 282467
UniProt P79105  
 S100A12 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for S100A12
Molecular Function
    calcium ion binding GO:0005509 IEA
    RAGE receptor binding GO:0050786 IEA
Biological Process
    positive regulation of canonical NF-kappaB signal transduction GO:0043123 IEA
    endothelial cell migration GO:0043542 IEA
    antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified S100A12 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for S100A12
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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