Gene description for ALOX15
Gene name arachidonate 15-lipoxygenase
Gene symbol ALOX15
Other names/aliases 15-LOX
ALOX12
Species Bos taurus
 Database cross references - ALOX15
ExoCarta ExoCarta_282139
Vesiclepedia VP_282139
Entrez Gene 282139
UniProt P27479  
 ALOX15 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ALOX15
Molecular Function
    arachidonate 12(S)-lipoxygenase activity GO:0004052 IEA
    iron ion binding GO:0005506 IEA
    protein binding GO:0005515 IEA
    arachidonate 15-lipoxygenase activity GO:0050473 IEA
Biological Process
    lipid oxidation GO:0034440 IEA
    linoleic acid metabolic process GO:0043651 IEA
Subcellular Localization
    cytosol GO:0005829 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified ALOX15 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ALOX15
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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