Gene description for HSPA8
Gene name	heat shock 70kDa protein 8
Gene symbol	HSPA8
Other names/aliases	HSPA10 Hsc70
Species	Bos taurus
Database cross references - HSPA8
ExoCarta	ExoCarta_281831
Entrez Gene	281831
UniProt	P19120
HSPA8 identified in exosomes derived from the following tissue/cell type
Milk	23459212

Gene ontology annotations for HSPA8

Molecular Function     ATPase activity, coupled GO:0042623 IEA     unfolded protein binding GO:0051082 IEA     MHC class II protein complex binding GO:0023026 IEA     protein binding GO:0005515 IPI     heat shock protein binding GO:0031072 IEA     ATP binding GO:0005524 IEA     poly(A) RNA binding GO:0044822 IEA     ubiquitin protein ligase binding GO:0031625 IEA     G-protein coupled receptor binding GO:0001664 IEA Biological Process     mRNA processing GO:0006397 IEA     RNA splicing GO:0008380 IEA     chaperone mediated protein folding requiring cofactor GO:0051085 IEA     clathrin coat disassembly GO:0072318 IEA     negative regulation of transcription, DNA-templated GO:0045892 ISS     protein refolding GO:0042026 IEA     regulation of cell cycle GO:0051726 IEA     transcription, DNA-templated GO:0006351 IEA     positive regulation of mRNA splicing, via spliceosome GO:0048026 IEA     negative regulation of fibril organization GO:1902904 IEA Subcellular Localization     melanosome GO:0042470 IEA     focal adhesion GO:0005925 IEA     cytosol GO:0005829 IEA     nucleolus GO:0005730 IEA     Prp19 complex GO:0000974 ISS     ribonucleoprotein complex GO:0030529 ISS     blood microparticle GO:0072562 IEA     ubiquitin ligase complex GO:0000151 IEA     plasma membrane GO:0005886 IEA     extracellular exosome GO:0070062 IEA     nucleus GO:0005634 ISS     spliceosomal complex GO:0005681 IEA