Gene description for GNAI2
Gene name guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Gene symbol GNAI2
Other names/aliases -
Species Bos taurus
 Database cross references - GNAI2
ExoCarta ExoCarta_281791
Vesiclepedia VP_281791
Entrez Gene 281791
 GNAI2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GNAI2
Molecular Function
    G protein-coupled receptor binding GO:0001664 IEA
    GTPase activity GO:0003924 IEA
    GTP binding GO:0005525 IEA
    G-protein beta/gamma-subunit complex binding GO:0031683 IEA
Biological Process
    adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO:0007188 IEA
    gamma-aminobutyric acid signaling pathway GO:0007214 IEA
Subcellular Localization
    heterotrimeric G-protein complex GO:0005834 IEA
 Experiment description of studies that identified GNAI2 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GNAI2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RGS4  
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which GNAI2 is involved
No pathways found





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