Gene description for CLTB
Gene name clathrin, light chain B
Gene symbol CLTB
Other names/aliases CLTLB
Species Bos taurus
 Database cross references - CLTB
ExoCarta ExoCarta_281698
Entrez Gene 281698
UniProt P04975  
 CLTB identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CLTB
Molecular Function
    structural molecule activity GO:0005198 IBA
    clathrin heavy chain binding GO:0032050 IBA
    protein binding GO:0005515 IPI
Biological Process
    clathrin-mediated endocytosis GO:0072583 IBA
    intracellular protein transport GO:0006886 IEA
Subcellular Localization
    clathrin coat of coated pit GO:0030132 IEA
    clathrin coat GO:0030118 ISS
    clathrin vesicle coat GO:0030125 IBA
    clathrin coat of trans-Golgi network vesicle GO:0030130 IEA
 Experiment description of studies that identified CLTB in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CLTB
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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