Gene description for GOT1
Gene name glutamic-oxaloacetic transaminase 1, soluble
Gene symbol GOT1
Other names/aliases cAspAT
cCAT
Species Bos taurus
 Database cross references - GOT1
ExoCarta ExoCarta_281206
Entrez Gene 281206
UniProt P33097  
 GOT1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GOT1
Molecular Function
    L-phenylalanine:2-oxoglutarate aminotransferase activity GO:0080130 IEA
    L-cysteine:2-oxoglutarate aminotransferase activity GO:0047801 ISS
    phosphatidylserine decarboxylase activity GO:0004609 IEA
    pyridoxal phosphate binding GO:0030170 IEA
    L-aspartate:2-oxoglutarate aminotransferase activity GO:0004069 IEA
Biological Process
    aspartate catabolic process GO:0006533 IEA
    cellular response to insulin stimulus GO:0032869 IEA
    oxaloacetate metabolic process GO:0006107 IEA
    aspartate biosynthetic process GO:0006532 IEA
    glutamate catabolic process to 2-oxoglutarate GO:0019551 IEA
    fatty acid homeostasis GO:0055089 IEA
    response to glucocorticoid GO:0051384 IEA
    glutamate catabolic process to aspartate GO:0019550 IEA
    glycerol biosynthetic process GO:0006114 ISS
Subcellular Localization
    cytosol GO:0005829 IEA
    extracellular exosome GO:0070062 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified GOT1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GOT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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