Gene description for ACTB
Gene name actin, beta
Gene symbol ACTB
Other names/aliases -
Species Bos taurus
 Database cross references - ACTB
ExoCarta ExoCarta_280979
Entrez Gene 280979
UniProt P60712  
 ACTB identified in exosomes derived from the following tissue/cell type
Tracheobronchial cells 19190083    
 Gene ontology annotations for ACTB
Molecular Function
    ATP binding GO:0005524 IEA
Biological Process
    chaperone mediated protein folding independent of cofactor GO:0051086 TAS
    protein folding GO:0006457 TAS
Subcellular Localization
    plasma membrane GO:0005886 ISS
    cytoskeleton GO:0005856 IEA
    cytosol GO:0005829 TAS
    NuA4 histone acetyltransferase complex GO:0035267 ISS
 Experiment description of studies that identified ACTB in exosomes
1
Experiment ID 34
ISEV standards
✔
EM|IEM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD63|MHCI|MHCII
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19190083    
Organism Homo sapiens
Experiment description Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
Authors Kesimer M, Scull M, Brighton B, Demaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK
Journal name FASEB
Publication year 2009
Sample Tracheobronchial cells
Sample name Tracheobronchial epithelial cells
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.16 -1.18 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
FACS
 Protein-protein interactions for ACTB
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ACTB is involved
PathwayEvidenceSource
Prefoldin mediated transfer of substrate to CCT/TriC IEA Reactome





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