Gene description for LTF
Gene name lactotransferrin
Gene symbol LTF
Other names/aliases Lf
Species Bos taurus
 Database cross references - LTF
ExoCarta ExoCarta_280846
Vesiclepedia VP_280846
Entrez Gene 280846
UniProt P24627  
 LTF identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LTF
Molecular Function
    serine-type endopeptidase activity GO:0004252 IEA
    iron ion binding GO:0005506 IEA
Biological Process
    regulation of cytokine production GO:0001817 IEA
    iron ion transport GO:0006826 IEA
    antibacterial humoral response GO:0019731 IEA
    antifungal humoral response GO:0019732 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    extracellular space GO:0005615 IEA
    early endosome GO:0005769 IEA
    plasma membrane GO:0005886 IEA
    recycling endosome GO:0055037 IEA
 Experiment description of studies that identified LTF in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LTF
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Traf6  
Affinity Capture-Western Mus musculus
View the network image/svg+xml



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