Gene description for PPA1
Gene name pyrophosphatase (inorganic) 1
Gene symbol PPA1
Other names/aliases PP
Species Bos taurus
 Database cross references - PPA1
ExoCarta ExoCarta_280701
Vesiclepedia VP_280701
Entrez Gene 280701
UniProt P37980  
 PPA1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PPA1
Molecular Function
    magnesium ion binding GO:0000287 IEA
    inorganic diphosphate phosphatase activity GO:0004427 IEA
Biological Process
    phosphate-containing compound metabolic process GO:0006796 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified PPA1 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PPA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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