Gene description for HP
Gene name haptoglobin
Gene symbol HP
Other names/aliases -
Species Bos taurus
 Database cross references - HP
ExoCarta ExoCarta_280692
Entrez Gene 280692
UniProt Q2TBU0  
 HP identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HP
Molecular Function
    hemoglobin binding GO:0030492 IEA
    antioxidant activity GO:0016209 IEA
Biological Process
    immune system process GO:0002376 IEA
    defense response to bacterium GO:0042742 IEA
    acute-phase response GO:0006953 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified HP in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HP
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HP is involved
No pathways found





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