Gene description for Tbcel
Gene name tubulin folding cofactor E-like
Gene symbol Tbcel
Other names/aliases D330014K23
E130107N23Rik
Lrrc35
Species Mus musculus
 Database cross references - Tbcel
ExoCarta ExoCarta_272589
Vesiclepedia VP_272589
Entrez Gene 272589
UniProt Q8C5W3  
 Tbcel identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Tbcel
Molecular Function
    alpha-tubulin binding GO:0043014 IBA
Biological Process
    microtubule cytoskeleton organization GO:0000226 IBA
    tubulin complex assembly GO:0007021 IBA
    post-chaperonin tubulin folding pathway GO:0007023 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IEA
    cytoskeleton GO:0005856 IEA
 Experiment description of studies that identified Tbcel in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Tbcel
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Tbcel is involved
No pathways found





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