Gene description for B3gnt6
Gene name UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
Gene symbol B3gnt6
Other names/aliases BC039789
Core-3
Core3
Species Mus musculus
 Database cross references - B3gnt6
ExoCarta ExoCarta_272411
Vesiclepedia VP_272411
Entrez Gene 272411
UniProt Q3USF0  
 B3gnt6 identified in sEVs derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for B3gnt6
Molecular Function
    UDP-glycosyltransferase activity GO:0008194 IBA
    galactosyltransferase activity GO:0008378 IBA
    galactosyltransferase activity GO:0008378 IEA
    galactosyltransferase activity GO:0008378 ISO
    acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity GO:0047224 IEA
Biological Process
    protein glycosylation GO:0006486 IEA
    protein O-linked glycosylation GO:0006493 IBA
    poly-N-acetyllactosamine biosynthetic process GO:0030311 IBA
Subcellular Localization
    Golgi membrane GO:0000139 IBA
    Golgi membrane GO:0000139 IEA
 Experiment description of studies that identified B3gnt6 in sEVs
1
Experiment ID 264
MISEV standards
✘ Biophysical techniques
✔
CD63|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-? via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors "Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino"
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for B3gnt6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 B3galt2  
Co-fractionation Mus musculus
View the network image/svg+xml



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