Experiment description of studies that identified TENM4 in sEVs

1 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

2 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for TENM4

Protein Interactor ExoCarta ID Identification method PubMed Species 1 LCE3D   Two-hybrid Homo sapiens 2 ZNF587   Two-hybrid Homo sapiens 3 SUB1 10923 Cross-Linking-MS (XL-MS) Homo sapiens 4 HOXB9   Two-hybrid Homo sapiens 5 PLSCR4   Two-hybrid Homo sapiens 6 C19orf66   Two-hybrid Homo sapiens 7 LGALS4 3960 Two-hybrid Homo sapiens 8 PGK1 5230 Cross-Linking-MS (XL-MS) Homo sapiens 9 DOCK2 1794 Two-hybrid Homo sapiens 10 CAND1 55832 Affinity Capture-MS Homo sapiens 11 FBXO6 26270 Affinity Capture-MS Homo sapiens 12 ZNF696   Two-hybrid Homo sapiens View the network

Pathways in which TENM4 is involved

No pathways found