Gene description for Gckr
Gene name	glucokinase (hexokinase 4) regulator
Gene symbol	Gckr
Other names/aliases	GLRE
Species	Rattus norvegicus
Database cross references - Gckr
ExoCarta	ExoCarta_25658
Vesiclepedia	VP_25658
Entrez Gene	25658
UniProt	Q07071
Gckr identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Gckr

Molecular Function     enzyme inhibitor activity GO:0004857 IDA     protein binding GO:0005515 IPI     kinase inhibitor activity GO:0019210 IBA     kinase inhibitor activity GO:0019210 IDA     kinase inhibitor activity GO:0019210 ISO     enzyme binding GO:0019899 IMP     enzyme binding GO:0019899 IPI     kinase binding GO:0019900 IPI     protein domain specific binding GO:0019904 IPI     carbohydrate binding GO:0030246 IDA     carbohydrate binding GO:0030246 IMP     fructose-6-phosphate binding GO:0070095 IBA     fructose-6-phosphate binding GO:0070095 ISO     fructose-6-phosphate binding GO:0070095 ISS     glucose sensor activity GO:0141089 IBA     glucose sensor activity GO:0141089 IDA     glucose sensor activity GO:0141089 ISO Biological Process     intracellular glucose homeostasis GO:0001678 IBA     intracellular glucose homeostasis GO:0001678 ISO     glucose metabolic process GO:0006006 TAS     protein import into nucleus GO:0006606 IDA     protein import into nucleus GO:0006606 ISO     response to glucose GO:0009749 IDA     response to glucose GO:0009749 ISO     response to fructose GO:0009750 IDA     response to fructose GO:0009750 ISO     negative regulation of glucokinase activity GO:0033132 ISO     negative regulation of glucokinase activity GO:0033132 ISO     positive regulation of glucokinase activity GO:0033133 ISO     protein localization to nucleus GO:0034504 IBA     protein localization to nucleus GO:0034504 ISO     urate metabolic process GO:0046415 ISO     triglyceride homeostasis GO:0070328 ISO     carbohydrate derivative metabolic process GO:1901135 IEA     negative regulation of hexokinase activity GO:1903300 IDA Subcellular Localization     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 IBA     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 IDA     mitochondrion GO:0005739 IEA     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO