Gene description for Icam1
Gene name	intercellular adhesion molecule 1
Gene symbol	Icam1
Other names/aliases	CD54 ICAM
Species	Rattus norvegicus
Database cross references - Icam1
ExoCarta	ExoCarta_25464
Vesiclepedia	VP_25464
Entrez Gene	25464
UniProt	Q00238
Icam1 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Icam1

Molecular Function     integrin binding GO:0005178 IBA     integrin binding GO:0005178 IEA     integrin binding GO:0005178 IMP     integrin binding GO:0005178 ISO     protein-containing complex binding GO:0044877 IPI Biological Process     ovarian follicle development GO:0001541 IEP     response to hypoxia GO:0001666 IEP     response to amphetamine GO:0001975 IEP     T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:0002291 ISO     acute inflammatory response to antigenic stimulus GO:0002438 IMP     T cell antigen processing and presentation GO:0002457 ISO     positive regulation of cellular extravasation GO:0002693 ISO     cell adhesion GO:0007155 IBA     cell adhesion GO:0007155 ISO     cell adhesion GO:0007155 ISO     leukocyte cell-cell adhesion GO:0007159 ISO     leukocyte cell-cell adhesion GO:0007159 ISO     regulation of cell shape GO:0008360 IMP     response to xenobiotic stimulus GO:0009410 IEP     response to ionizing radiation GO:0010212 IEP     response to sulfur dioxide GO:0010477 IEP     response to organic cyclic compound GO:0014070 IEP     membrane to membrane docking GO:0022614 ISO     positive regulation of actin filament polymerization GO:0030838 IDA     cellular response to nutrient levels GO:0031669 IEP     response to lipopolysaccharide GO:0032496 IEP     response to insulin GO:0032868 IEP     cell adhesion mediated by integrin GO:0033627 ISO     response to gonadotropin GO:0034698 IEP     response to amino acid GO:0043200 IEP     positive regulation of GTPase activity GO:0043547 IDA     positive regulation of nitric oxide biosynthetic process GO:0045429 IMP     response to ethanol GO:0045471 IEP     positive regulation of vasoconstriction GO:0045907 IMP     regulation of activated T cell proliferation GO:0046006 ISO     response to copper ion GO:0046688 IEP     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IDA     leukocyte migration GO:0050900 ISO     leukocyte migration GO:0050900 TAS     positive regulation of NF-kappaB transcription factor activity GO:0051092 IMP     negative regulation of calcium ion transport GO:0051926 IDA     establishment of endothelial barrier GO:0061028 ISO     positive regulation of T cell apoptotic process GO:0070234 ISO     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     cellular response to lipopolysaccharide GO:0071222 IEP     cellular response to alkaloid GO:0071312 IEP     cellular response to glucose stimulus GO:0071333 IEP     cellular response to glucose stimulus GO:0071333 ISO     cellular response to type II interferon GO:0071346 IEP     cellular response to interleukin-1 GO:0071347 IEP     cellular response to interleukin-6 GO:0071354 IEP     cellular response to tumor necrosis factor GO:0071356 IEP     cellular response to hypoxia GO:0071456 IEP     cellular response to dexamethasone stimulus GO:0071549 IEP     T cell extravasation GO:0072683 ISO     cellular senescence GO:0090398 IEP     establishment of endothelial intestinal barrier GO:0090557 IMP     establishment of Sertoli cell barrier GO:0097368 IDA     cell-cell adhesion GO:0098609 IDA     cell-cell adhesion GO:0098609 IEA     cell-cell adhesion GO:0098609 IMP     regulation of ruffle assembly GO:1900027 ISO     negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 ISO     response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine GO:1904316 IEP     cellular response to amyloid-beta GO:1904646 ISO     positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 IMP     cellular response to leukemia inhibitory factor GO:1990830 ISO     negative regulation of endothelial cell apoptotic process GO:2000352 ISO Subcellular Localization     immunological synapse GO:0001772 ISO     extracellular space GO:0005615 IDA     extracellular space GO:0005615 ISO     plasma membrane GO:0005886 IBA     external side of plasma membrane GO:0009897 ISO     cell surface GO:0009986 IDA     membrane GO:0016020 IEA     membrane raft GO:0045121 ISO     extracellular exosome GO:0070062 ISO