Gene description for Acox2
Gene name acyl-CoA oxidase 2, branched chain
Gene symbol Acox2
Other names/aliases THCCox
Species Rattus norvegicus
 Database cross references - Acox2
ExoCarta ExoCarta_252898
Vesiclepedia VP_252898
Entrez Gene 252898
 Acox2 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Acox2
Molecular Function
    acyl-CoA oxidase activity GO:0003997 IEA
    fatty acid binding GO:0005504 IBA
    fatty acid binding GO:0005504 IDA
    fatty acid binding GO:0005504 IEA
    palmitoyl-CoA oxidase activity GO:0016401 IBA
    3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity GO:0033791 IBA
    3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity GO:0033791 IDA
    3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity GO:0033791 IEA
    3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity GO:0033791 ISO
    flavin adenine dinucleotide binding GO:0050660 IBA
    flavin adenine dinucleotide binding GO:0050660 IDA
    FAD binding GO:0071949 IEA
Biological Process
    very long-chain fatty acid metabolic process GO:0000038 IBA
    fatty acid metabolic process GO:0006631 IEP
    fatty acid beta-oxidation GO:0006635 IDA
    bile acid biosynthetic process GO:0006699 IEA
    bile acid biosynthetic process GO:0006699 ISO
    bile acid biosynthetic process GO:0006699 ISS
    fatty acid beta-oxidation using acyl-CoA oxidase GO:0033540 IBA
    fatty acid beta-oxidation using acyl-CoA oxidase GO:0033540 IEA
    fatty acid beta-oxidation using acyl-CoA oxidase GO:0033540 ISO
Subcellular Localization
    peroxisome GO:0005777 IBA
    peroxisome GO:0005777 IDA
    peroxisome GO:0005777 IEA
    peroxisome GO:0005777 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Acox2 in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Acox2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Acox2 is involved
No pathways found





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