Gene description for Adam34
Gene name a disintegrin and metallopeptidase domain 34
Gene symbol Adam34
Other names/aliases -
Species Mus musculus
 Database cross references - Adam34
ExoCarta ExoCarta_252866
Vesiclepedia VP_252866
Entrez Gene 252866
 Adam34 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Adam34
Molecular Function
    molecular_function GO:0003674 ND
    metalloendopeptidase activity GO:0004222 IBA
Biological Process
    proteolysis GO:0006508 IBA
    male gonad development GO:0008584 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    external side of plasma membrane GO:0009897 IBA
    sperm head plasma membrane GO:1990913 IBA
 Experiment description of studies that identified Adam34 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Adam34
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Adam34 is involved
No pathways found





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