Gene description for Dpp4
Gene name	dipeptidylpeptidase 4
Gene symbol	Dpp4
Other names/aliases	CD26 DPPIV
Species	Rattus norvegicus
Database cross references - Dpp4
ExoCarta	ExoCarta_25253
Vesiclepedia	VP_25253
Entrez Gene	25253
UniProt	P14740
Dpp4 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702
Urine	20535238

Gene ontology annotations for Dpp4

Molecular Function     virus receptor activity GO:0001618 ISO     protease binding GO:0002020 ISO     protease binding GO:0002020 ISS     aminopeptidase activity GO:0004177 IEA     serine-type endopeptidase activity GO:0004252 IEA     serine-type endopeptidase activity GO:0004252 ISO     signaling receptor binding GO:0005102 ISO     signaling receptor binding GO:0005102 ISS     collagen binding GO:0005518 IDA     serine-type peptidase activity GO:0008236 ISO     dipeptidyl-peptidase activity GO:0008239 IBA     dipeptidyl-peptidase activity GO:0008239 IDA     dipeptidyl-peptidase activity GO:0008239 IEA     dipeptidyl-peptidase activity GO:0008239 IMP     dipeptidyl-peptidase activity GO:0008239 ISO     dipeptidyl-peptidase activity GO:0008239 ISS     peptide binding GO:0042277 IDA     identical protein binding GO:0042802 IMP     identical protein binding GO:0042802 IPI     identical protein binding GO:0042802 ISO     protein homodimerization activity GO:0042803 ISO     protein homodimerization activity GO:0042803 ISS     chemorepellent activity GO:0045499 ISO Biological Process     behavioral fear response GO:0001662 ISO     response to hypoxia GO:0001666 ISO     B-1a B cell differentiation GO:0002337 IMP     regulation of T cell mediated immunity GO:0002709 IMP     positive regulation of natural killer cell mediated immunity GO:0002717 IMP     proteolysis GO:0006508 IBA     proteolysis GO:0006508 IEA     proteolysis GO:0006508 ISO     proteolysis GO:0006508 TAS     cell adhesion GO:0007155 IEA     positive regulation of cell population proliferation GO:0008284 ISO     positive regulation of cell population proliferation GO:0008284 ISS     negative regulation of extracellular matrix disassembly GO:0010716 ISO     negative regulation of extracellular matrix disassembly GO:0010716 ISS     protein catabolic process GO:0030163 IDA     T cell costimulation GO:0031295 ISO     T cell costimulation GO:0031295 ISS     regulation of cell-cell adhesion mediated by integrin GO:0033632 ISO     locomotory exploration behavior GO:0035641 ISO     psychomotor behavior GO:0036343 ISO     T cell activation GO:0042110 ISO     endothelial cell migration GO:0043542 ISO     endothelial cell migration GO:0043542 ISS     symbiont entry into host cell GO:0046718 IEA     negative chemotaxis GO:0050919 IEA     negative regulation of neutrophil chemotaxis GO:0090024 ISO Subcellular Localization     extracellular region GO:0005576 IEA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 ISO     cell surface GO:0009986 IDA     cell surface GO:0009986 ISO     cell surface GO:0009986 ISS     apical plasma membrane GO:0016324 IEA     apical plasma membrane GO:0016324 ISO     lamellipodium GO:0030027 ISO     lamellipodium GO:0030027 ISS     endocytic vesicle GO:0030139 ISO     endocytic vesicle GO:0030139 ISS     lamellipodium membrane GO:0031258 IEA     membrane raft GO:0045121 IEA     intercellular canaliculus GO:0046581 ISO     anchoring junction GO:0070161 IEA