Gene description for Eef1a2
Gene name eukaryotic translation elongation factor 1 alpha 2
Gene symbol Eef1a2
Other names/aliases Ps10
RATPS10
Stnl
Species Rattus norvegicus
 Database cross references - Eef1a2
ExoCarta ExoCarta_24799
Vesiclepedia VP_24799
Entrez Gene 24799
UniProt P62632  
 Eef1a2 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Eef1a2
Molecular Function
    translation elongation factor activity GO:0003746 IBA
    translation elongation factor activity GO:0003746 ISO
    GTPase activity GO:0003924 IBA
    voltage-gated potassium channel activity GO:0005249 IEA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IEA
    protein kinase binding GO:0019901 ISO
Biological Process
    translation GO:0006412 IBA
    translational elongation GO:0006414 IBA
    translational elongation GO:0006414 ISO
    positive regulation of apoptotic process GO:0043065 ISO
    response to electrical stimulus GO:0051602 IEP
    potassium ion transmembrane transport GO:0071805 IEA
    positive regulation of lipid kinase activity GO:0090218 ISO
    regulation of postsynaptic specialization assembly GO:0099150 IDA
    regulation of postsynaptic specialization assembly GO:0099150 IMP
Subcellular Localization
    nucleus GO:0005634 IEA
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 ISO
    eukaryotic translation elongation factor 1 complex GO:0005853 ISO
    plasma membrane GO:0005886 IEA
    monoatomic ion channel complex GO:0034702 IEA
    neuronal cell body GO:0043025 IDA
    synapse GO:0045202 ISO
    GABA-ergic synapse GO:0098982 IDA
    GABA-ergic synapse GO:0098982 IMP
 Experiment description of studies that identified Eef1a2 in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Eef1a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Dao  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Eef1a2 is involved
No pathways found





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