Gene description for Sod2
Gene name	superoxide dismutase 2, mitochondrial
Gene symbol	Sod2
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Sod2
ExoCarta	ExoCarta_24787
Entrez Gene	24787
UniProt	P07895
Sod2 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Sod2

Molecular Function     oxygen binding GO:0019825 IDA     protein binding GO:0005515 IPI     identical protein binding GO:0042802 ISO     superoxide dismutase activity GO:0004784 ISS     manganese ion binding GO:0030145 ISS     DNA binding GO:0003677 IDA Biological Process     age-dependent response to reactive oxygen species GO:0001315 ISS     response to superoxide GO:0000303 ISO     iron ion homeostasis GO:0055072 ISO     response to manganese ion GO:0010042 IEP     response to hydrogen peroxide GO:0042542 ISO     response to immobilization stress GO:0035902 IEP     negative regulation of fibroblast proliferation GO:0048147 ISO     protein homooligomerization GO:0051260 IDA     post-embryonic development GO:0009791 ISO     response to lipopolysaccharide GO:0032496 IEP     neuron development GO:0048666 ISO     response to L-ascorbic acid GO:0033591 IEP     response to hyperoxia GO:0055093 ISO     glutathione metabolic process GO:0006749 ISO     hydrogen peroxide metabolic process GO:0042743 IMP     response to hypoxia GO:0001666 IEP     hemopoiesis GO:0030097 ISO     response to electrical stimulus GO:0051602 IEP     response to cadmium ion GO:0046686 IEP     negative regulation of apoptotic process GO:0043066 IMP     erythrophore differentiation GO:0048773 ISO     intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 ISO     liver development GO:0001889 ISO     response to gamma radiation GO:0010332 ISO     age-dependent response to oxidative stress GO:0001306 ISO     protein homotetramerization GO:0051289 ISO     response to nutrient levels GO:0031667 IDA     detection of oxygen GO:0003032 ISO     release of cytochrome c from mitochondria GO:0001836 ISO     response to activity GO:0014823 ISO     aging GO:0007568 IEP     mitochondrion organization GO:0007005 ISO     response to selenium ion GO:0010269 IEP     vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure GO:0003069 ISO     hydrogen peroxide biosynthetic process GO:0050665 IDA     regulation of transcription from RNA polymerase II promoter GO:0006357 ISS     response to oxidative stress GO:0006979 ISO     intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 ISO     sensory perception of sound GO:0007605 ISO     locomotory behavior GO:0007626 ISO     heart development GO:0007507 ISO     regulation of blood pressure GO:0008217 ISO     response to isolation stress GO:0035900 IEP     vasodilation GO:0042311 ISO     superoxide anion generation GO:0042554 ISO     response to axon injury GO:0048678 ISO     response to drug GO:0042493 IDA     apoptotic mitochondrial changes GO:0008637 ISO     negative regulation of neuron apoptotic process GO:0043524 ISO     cellular response to ethanol GO:0071361 IEP     response to silicon dioxide GO:0034021 IEP     superoxide metabolic process GO:0006801 ISS     positive regulation of nitric oxide biosynthetic process GO:0045429 ISO     negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902176 ISO     removal of superoxide radicals GO:0019430 TAS     response to radiation GO:0009314 IEP     response to reactive oxygen species GO:0000302 ISO     negative regulation of fat cell differentiation GO:0045599 ISO     negative regulation of cell proliferation GO:0008285 ISO     respiratory electron transport chain GO:0022904 ISO     response to cold GO:0009409 IEP     oxygen homeostasis GO:0032364 ISO     regulation of mitochondrial membrane potential GO:0051881 ISO     response to magnetism GO:0071000 IEP     regulation of catalytic activity GO:0050790 ISO     response to zinc ion GO:0010043 IEP Subcellular Localization     mitochondrial inner membrane GO:0005743 ISO     mitochondrion GO:0005739 NAS     extracellular exosome GO:0070062 ISO     intracellular GO:0005622 ISO     cytoplasm GO:0005737 IDA     mitochondrial nucleoid GO:0042645 IDA     myelin sheath GO:0043209 ISO