Gene description for Slc10a1
Gene name solute carrier family 10 (sodium/bile acid cotransporter), member 1
Gene symbol Slc10a1
Other names/aliases Ntcp
Ntcp1
SBACT
Species Rattus norvegicus
 Database cross references - Slc10a1
ExoCarta ExoCarta_24777
Vesiclepedia VP_24777
Entrez Gene 24777
UniProt P26435  
 Slc10a1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Slc10a1
Molecular Function
    bile acid:sodium symporter activity GO:0008508 IBA
    bile acid:sodium symporter activity GO:0008508 IDA
    bile acid:sodium symporter activity GO:0008508 TAS
    bile acid transmembrane transporter activity GO:0015125 IDA
    bile acid transmembrane transporter activity GO:0015125 ISO
Biological Process
    sodium ion transport GO:0006814 IEA
    response to organic cyclic compound GO:0014070 IEP
    bile acid and bile salt transport GO:0015721 IBA
    bile acid and bile salt transport GO:0015721 IDA
    bile acid and bile salt transport GO:0015721 IEP
    response to nutrient levels GO:0031667 IEP
    response to estrogen GO:0043627 IEP
    response to ethanol GO:0045471 IEP
    transmembrane transport GO:0055085 IEA
    cellular response to xenobiotic stimulus GO:0071466 IEP
Subcellular Localization
    plasma membrane GO:0005886 ISO
    membrane GO:0016020 ISO
    basolateral plasma membrane GO:0016323 IDA
 Experiment description of studies that identified Slc10a1 in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Slc10a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here