Gene description for Slc10a1
Gene name solute carrier family 10 (sodium/bile acid cotransporter), member 1
Gene symbol Slc10a1
Other names/aliases Ntcp
Ntcp1
SBACT
Species Rattus norvegicus
 Database cross references - Slc10a1
ExoCarta ExoCarta_24777
Vesiclepedia VP_24777
Entrez Gene 24777
UniProt P26435  
 Slc10a1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Slc10a1
Molecular Function
    bile acid:sodium symporter activity GO:0008508 IBA
    bile acid:sodium symporter activity GO:0008508 IDA
    bile acid:sodium symporter activity GO:0008508 TAS
    bile acid transmembrane transporter activity GO:0015125 IDA
    bile acid transmembrane transporter activity GO:0015125 ISO
Biological Process
    sodium ion transport GO:0006814 IEA
    response to organic cyclic compound GO:0014070 IEP
    bile acid and bile salt transport GO:0015721 IBA
    bile acid and bile salt transport GO:0015721 IDA
    bile acid and bile salt transport GO:0015721 IEP
    response to nutrient levels GO:0031667 IEP
    response to estrogen GO:0043627 IEP
    response to ethanol GO:0045471 IEP
    transmembrane transport GO:0055085 IEA
    cellular response to xenobiotic stimulus GO:0071466 IEP
Subcellular Localization
    plasma membrane GO:0005886 ISO
    membrane GO:0016020 ISO
    basolateral plasma membrane GO:0016323 IDA
 Experiment description of studies that identified Slc10a1 in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Slc10a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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