|
 Gene description for Lgals3bp |
| Gene name |
lectin, galactoside-binding, soluble, 3 binding protein |
| Gene symbol |
Lgals3bp |
| Other names/aliases |
CyCAP
MAC2BP
Ppicap
mama |
| Species |
Rattus norvegicus |
| Database cross references - Lgals3bp |
| ExoCarta |
ExoCarta_245955 |
| Vesiclepedia |
VP_245955 |
| Entrez Gene |
245955 |
| UniProt |
O70513
|
| Lgals3bp identified in sEVs derived from the following tissue/cell type |
|
Pancreatic cancer cells
|
20124479
|
|
Pancreatic cancer cells
|
20124479
|
|
Reticulocytes
|
21828046
|
|
Reticulocytes
|
21828046
|
| Gene ontology annotations for Lgals3bp |
|
|
| Experiment description of studies that identified Lgals3bp in sEVs |
| 1 |
| Experiment ID |
92 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
HSP70|GAPDH|CD9|CD151
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Western blotting
|
| PubMed ID |
20124479
|
| Organism |
Rattus norvegicus |
| Experiment description |
Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. |
| Authors |
"Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M." |
| Journal name |
CR
|
| Publication year |
2010 |
| Sample |
Pancreatic cancer cells |
| Sample name |
AS |
| Isolation/purification methods |
Differential centrifugation
Sucrose density gradient |
| Flotation density |
1.14-1.17 g/mL
|
| Molecules identified in the study |
Protein
mRNA |
| Methods used in the study |
RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF] |
|
|
| 2 |
| Experiment ID |
93 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
HSP70|GAPDH|CD9|CD151
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Western blotting
Mass spectrometry [MALDI TOF]
|
| PubMed ID |
20124479
|
| Organism |
Rattus norvegicus |
| Experiment description |
Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. |
| Authors |
"Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M." |
| Journal name |
CR
|
| Publication year |
2010 |
| Sample |
Pancreatic cancer cells |
| Sample name |
AS-Tspan8 |
| Isolation/purification methods |
Differential centrifugation
Sucrose density gradient |
| Flotation density |
1.14-1.17 g/mL
|
| Molecules identified in the study |
Protein
mRNA |
| Methods used in the study |
RT-PCR
Western blotting |
|
|
| 3 |
| Experiment ID |
90 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
HSC70|HSP90|TSG101|MHCI
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry [Orbitrap]
|
| PubMed ID |
21828046
|
| Organism |
Rattus norvegicus |
| Experiment description |
The proteo-lipidic composition of exosomes changes during reticulocyte maturation. |
| Authors |
"Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E" |
| Journal name |
JBC
|
| Publication year |
2011 |
| Sample |
Reticulocytes |
| Sample name |
Reticulocytes - D2 Rep 1 |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
1.16-1.21 g/mL
|
| Molecules identified in the study |
Protein
Lipids |
| Methods used in the study |
Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting |
|
|
| 4 |
| Experiment ID |
96 |
| MISEV standards |
|
✔
EM
|
Biophysical techniques |
|
✔
TSG101|HSP90|HSC70|MHCI
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry [Orbitrap]
|
| PubMed ID |
21828046
|
| Organism |
Rattus norvegicus |
| Experiment description |
The proteo-lipidic composition of exosomes changes during reticulocyte maturation. |
| Authors |
"Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E." |
| Journal name |
JBC
|
| Publication year |
2011 |
| Sample |
Reticulocytes |
| Sample name |
Reticulocytes - D2 Rep 2 |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
1.16-1.21 g/mL
|
| Molecules identified in the study |
Protein
Lipids |
| Methods used in the study |
Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting |
|
|
| Protein-protein interactions for Lgals3bp |
| |
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
|
No interactions are found.
|
|
| Pathways in which Lgals3bp is involved |
|
|
|
