Gene description for Gstp1
Gene name	glutathione S-transferase pi 1
Gene symbol	Gstp1
Other names/aliases	GST-P Gst3 Gstp Gstp2
Species	Rattus norvegicus
Database cross references - Gstp1
ExoCarta	ExoCarta_24426
Vesiclepedia	VP_24426
Entrez Gene	24426
UniProt	P04906
Gstp1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Urine	20535238

Gene ontology annotations for Gstp1

Molecular Function     glutathione transferase activity GO:0004364 IBA     glutathione transferase activity GO:0004364 ISO     glutathione peroxidase activity GO:0004602 ISO     fatty acid binding GO:0005504 ISO     JUN kinase binding GO:0008432 ISO     JUN kinase binding GO:0008432 ISS     toxic substance binding GO:0015643 IPI     kinase regulator activity GO:0019207 ISO     kinase regulator activity GO:0019207 ISS     protein kinase binding GO:0019901 IPI     S-nitrosoglutathione binding GO:0035730 ISO     dinitrosyl-iron complex binding GO:0035731 ISO     organic cyclic compound binding GO:0097159 IPI Biological Process     response to reactive oxygen species GO:0000302 ISO     response to reactive oxygen species GO:0000302 ISS     negative regulation of protein kinase activity GO:0006469 IMP     negative regulation of protein kinase activity GO:0006469 ISO     prostaglandin metabolic process GO:0006693 ISO     prostaglandin metabolic process GO:0006693 ISS     glutathione metabolic process GO:0006749 IBA     glutathione metabolic process GO:0006749 ISO     glutathione metabolic process GO:0006749 ISO     xenobiotic metabolic process GO:0006805 ISO     xenobiotic metabolic process GO:0006805 TAS     response to toxic substance GO:0009636 IEP     negative regulation of biosynthetic process GO:0009890 ISO     oligodendrocyte development GO:0014003 IEP     animal organ regeneration GO:0031100 IEP     response to nutrient levels GO:0031667 IEP     response to estradiol GO:0032355 IEP     negative regulation of interleukin-1 beta production GO:0032691 ISO     negative regulation of interleukin-1 beta production GO:0032691 ISS     negative regulation of tumor necrosis factor production GO:0032720 ISO     negative regulation of tumor necrosis factor production GO:0032720 ISS     cellular response to insulin stimulus GO:0032869 IEP     regulation of stress-activated MAPK cascade GO:0032872 ISO     regulation of stress-activated MAPK cascade GO:0032872 ISS     negative regulation of stress-activated MAPK cascade GO:0032873 ISO     negative regulation of stress-activated MAPK cascade GO:0032873 ISS     positive regulation of superoxide anion generation GO:0032930 ISO     positive regulation of superoxide anion generation GO:0032930 ISS     response to L-ascorbic acid GO:0033591 IEP     common myeloid progenitor cell proliferation GO:0035726 ISO     common myeloid progenitor cell proliferation GO:0035726 ISS     negative regulation of canonical NF-kappaB signal transduction GO:0043124 ISO     negative regulation of canonical NF-kappaB signal transduction GO:0043124 ISS     response to amino acid GO:0043200 IEP     negative regulation of MAP kinase activity GO:0043407 ISO     negative regulation of JUN kinase activity GO:0043508 ISO     linoleic acid metabolic process GO:0043651 ISO     response to ethanol GO:0045471 IEP     negative regulation of fibroblast proliferation GO:0048147 ISO     negative regulation of fibroblast proliferation GO:0048147 ISS     hepoxilin biosynthetic process GO:0051122 ISO     hepoxilin biosynthetic process GO:0051122 ISS     regulation of ERK1 and ERK2 cascade GO:0070372 ISO     regulation of ERK1 and ERK2 cascade GO:0070372 ISS     negative regulation of ERK1 and ERK2 cascade GO:0070373 ISO     negative regulation of ERK1 and ERK2 cascade GO:0070373 ISS     negative regulation of leukocyte proliferation GO:0070664 ISO     negative regulation of leukocyte proliferation GO:0070664 ISS     cellular response to lipopolysaccharide GO:0071222 ISO     cellular response to lipopolysaccharide GO:0071222 ISS     cellular response to epidermal growth factor stimulus GO:0071364 IEP     cellular response to glucocorticoid stimulus GO:0071385 IEP     cellular response to cell-matrix adhesion GO:0071460 IEP     negative regulation of monocyte chemotactic protein-1 production GO:0071638 ISO     negative regulation of monocyte chemotactic protein-1 production GO:0071638 ISS     negative regulation of smooth muscle cell chemotaxis GO:0071672 IMP     cellular oxidant detoxification GO:0098869 IEA     glutathione derivative biosynthetic process GO:1901687 ISO     glutathione derivative biosynthetic process GO:1901687 ISS     negative regulation of vascular associated smooth muscle cell proliferation GO:1904706 IMP     negative regulation of extrinsic apoptotic signaling pathway GO:2001237 ISO Subcellular Localization     nucleus GO:0005634 IEA     mitochondrion GO:0005739 IEA     mitochondrion GO:0005739 ISO     cytosol GO:0005829 IBA     cytosol GO:0005829 ISO     protein-containing complex GO:0032991 ISO     protein-containing complex GO:0032991 ISS     TRAF2-GSTP1 complex GO:0097057 ISO