Gene description for Fgb
Gene name	fibrinogen beta chain
Gene symbol	Fgb
Other names/aliases	Ab1-181 Ab1-216 Ac1-581
Species	Rattus norvegicus
Database cross references - Fgb
ExoCarta	ExoCarta_24366
Vesiclepedia	VP_24366
Entrez Gene	24366
UniProt	P14480
Fgb identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Fgb

Molecular Function     signaling receptor binding GO:0005102 IEA     signaling receptor binding GO:0005102 ISO     structural molecule activity GO:0005198 ISO     cell adhesion molecule binding GO:0050839 ISO     protein-folding chaperone binding GO:0051087 ISO Biological Process     adaptive immune response GO:0002250 IEA     cell-matrix adhesion GO:0007160 IBA     cell-matrix adhesion GO:0007160 ISO     platelet activation GO:0030168 IEA     plasminogen activation GO:0031639 ISO     positive regulation of heterotypic cell-cell adhesion GO:0034116 ISO     fibrinolysis GO:0042730 ISO     induction of bacterial agglutination GO:0043152 ISO     cellular response to leptin stimulus GO:0044320 IEP     innate immune response GO:0045087 IEA     positive regulation of vasoconstriction GO:0045907 ISO     positive regulation of exocytosis GO:0045921 ISO     positive regulation of protein secretion GO:0050714 ISO     protein polymerization GO:0051258 IEA     protein polymerization GO:0051258 ISO     response to calcium ion GO:0051592 ISO     protein-containing complex assembly GO:0065003 ISO     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     platelet aggregation GO:0070527 IBA     platelet aggregation GO:0070527 ISO     cellular response to interleukin-1 GO:0071347 IEP     blood coagulation, fibrin clot formation GO:0072378 IBA     blood coagulation, fibrin clot formation GO:0072378 ISO     positive regulation of peptide hormone secretion GO:0090277 ISO     negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 ISO     negative regulation of endothelial cell apoptotic process GO:2000352 ISO Subcellular Localization     fibrinogen complex GO:0005577 IEA     fibrinogen complex GO:0005577 ISO     extracellular space GO:0005615 IBA     extracellular space GO:0005615 ISO     endoplasmic reticulum GO:0005783 IEA     endoplasmic reticulum GO:0005783 ISO     cell cortex GO:0005938 ISO     external side of plasma membrane GO:0009897 ISO     cell surface GO:0009986 ISO     platelet alpha granule GO:0031091 ISO     synapse GO:0045202 ISO     collagen-containing extracellular matrix GO:0062023 IBA     blood microparticle GO:0072562 IDA