Gene description for Cp
Gene name ceruloplasmin (ferroxidase)
Gene symbol Cp
Other names/aliases CERP
Species Rattus norvegicus
 Database cross references - Cp
ExoCarta ExoCarta_24268
Vesiclepedia VP_24268
Entrez Gene 24268
 Cp identified in sEVs derived from the following tissue/cell type
Cortical neurones 16446100    
 Gene ontology annotations for Cp
Molecular Function
    ferroxidase activity GO:0004322 ISO
    ferroxidase activity GO:0004322 ISS
    glutathione peroxidase activity GO:0004602 ISO
    glutathione peroxidase activity GO:0004602 ISS
    copper ion binding GO:0005507 IDA
    copper ion binding GO:0005507 IEA
    copper ion binding GO:0005507 ISO
    oxidoreductase activity GO:0016491 IBA
    oxidoreductase activity GO:0016491 IEA
    oxidoreductase activity, acting on metal ions, oxygen as acceptor GO:0016724 ISO
    oxidoreductase activity, acting on metal ions, oxygen as acceptor GO:0016724 ISS
    phospholipid-hydroperoxide glutathione peroxidase activity GO:0047066 ISO
    phospholipid-hydroperoxide glutathione peroxidase activity GO:0047066 ISS
    protein-folding chaperone binding GO:0051087 ISO
Biological Process
    liver development GO:0001889 IEP
    iron ion transport GO:0006826 IBA
    intracellular copper ion homeostasis GO:0006878 ISO
    intracellular copper ion homeostasis GO:0006878 ISS
    intracellular iron ion homeostasis GO:0006879 ISO
    intracellular iron ion homeostasis GO:0006879 ISS
    intracellular iron ion homeostasis GO:0006879 TAS
    female pregnancy GO:0007565 IEP
    response to nutrient GO:0007584 IEP
    lactation GO:0007595 IEP
    plasma membrane copper ion transport GO:0015679 TAS
    lung development GO:0030324 IEP
    response to copper ion GO:0046688 IDA
    mammary gland involution GO:0060056 IEP
    cellular oxidant detoxification GO:0098869 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    extracellular space GO:0005615 IDA
    extracellular space GO:0005615 ISO
    plasma membrane GO:0005886 IBA
    cell surface GO:0009986 IDA
 Experiment description of studies that identified Cp in sEVs
1
Experiment ID 30
MISEV standards
EM
Biophysical techniques
Alix|TSG101|FLOT
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 16446100    
Organism Rattus norvegicus
Experiment description Exosomes are released by cultured cortical neurones.
Authors "Faure J, Lachenal G, Court M, Hirrlinger J, Chatellard-Causse C, Blot B, Grange J, Schoehn G, Goldberg Y, Boyer V, Kirchhoff F, Raposo G, Garin J, Sadoul R"
Journal name MCN
Publication year 2006
Sample Cortical neurones
Sample name Cortical neurones
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Cp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cp is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here