Gene description for Impad1
Gene name inositol monophosphatase domain containing 1
Gene symbol Impad1
Other names/aliases 1110001C20Rik
AA408880
AI451589
AL022796
B230207P20
Jaws
gPAPP
Species Mus musculus
 Database cross references - Impad1
ExoCarta ExoCarta_242291
Vesiclepedia VP_242291
Entrez Gene 242291
UniProt Q80V26  
 Impad1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Impad1
Molecular Function
    3'-nucleotidase activity GO:0008254 IBA
    3'-nucleotidase activity GO:0008254 IDA
    3'(2'),5'-bisphosphate nucleotidase activity GO:0008441 IEA
    metal ion binding GO:0046872 IEA
    3',5'-nucleotide bisphosphate phosphatase activity GO:0097657 IDA
Biological Process
    skeletal system development GO:0001501 IBA
    skeletal system development GO:0001501 IMP
    endochondral ossification GO:0001958 IMP
    chondrocyte development GO:0002063 IMP
    post-embryonic development GO:0009791 IMP
    chondroitin sulfate metabolic process GO:0030204 IMP
    embryonic digit morphogenesis GO:0042733 IMP
    phosphatidylinositol phosphate biosynthetic process GO:0046854 IEA
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    Golgi apparatus GO:0005794 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    endomembrane system GO:0012505 IBA
    nuclear body GO:0016604 IEA
    nuclear body GO:0016604 ISO
    trans-Golgi network membrane GO:0032588 IDA
 Experiment description of studies that identified Impad1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Impad1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fancd2  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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