Gene description for Asgr1
Gene name asialoglycoprotein receptor 1
Gene symbol Asgr1
Other names/aliases ASGR
RATRHL1
RHL1
Species Rattus norvegicus
 Database cross references - Asgr1
ExoCarta ExoCarta_24210
Entrez Gene 24210
UniProt P02706  
 Asgr1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Asgr1
Molecular Function
    carbohydrate binding GO:0030246 IEA
    protein homodimerization activity GO:0042803 ISO
    metal ion binding GO:0046872 IEA
    asialoglycoprotein receptor activity GO:0004873 IDA
Biological Process
    receptor-mediated endocytosis GO:0006898 IDA
    cellular response to extracellular stimulus GO:0031668 ISO
Subcellular Localization
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Asgr1 in exosomes
1
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Western blotting
Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Asgr1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Asgr1 is involved
No pathways found





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