Gene description for Adh1
Gene name alcohol dehydrogenase 1 (class I)
Gene symbol Adh1
Other names/aliases Adh
Adh1a
Adh1c
Species Rattus norvegicus
 Database cross references - Adh1
ExoCarta ExoCarta_24172
Vesiclepedia VP_24172
Entrez Gene 24172
UniProt P06757  
 Adh1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Adh1
Molecular Function
    alcohol dehydrogenase (NAD+) activity GO:0004022 IBA
    alcohol dehydrogenase (NAD+) activity GO:0004022 IDA
    alcohol dehydrogenase (NAD+) activity GO:0004022 IEA
    alcohol dehydrogenase (NAD+) activity GO:0004022 ISO
    alcohol dehydrogenase (NAD+) activity GO:0004022 TAS
    all-trans-retinol dehydrogenase (NAD+) activity GO:0004745 IBA
    all-trans-retinol dehydrogenase (NAD+) activity GO:0004745 IDA
    zinc ion binding GO:0008270 IBA
    zinc ion binding GO:0008270 IEA
    oxidoreductase activity GO:0016491 IEA
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    organic cyclic compound binding GO:0097159 IPI
Biological Process
    retinoid metabolic process GO:0001523 ISO
    ethanol catabolic process GO:0006068 IEA
    ethanol catabolic process GO:0006068 ISO
    lipid metabolic process GO:0006629 IDA
    animal organ regeneration GO:0031100 IEP
    response to retinoic acid GO:0032526 IEA
    response to retinoic acid GO:0032526 ISO
    response to progesterone GO:0032570 IEP
    response to testosterone GO:0033574 IEA
    response to testosterone GO:0033574 ISO
    retinol metabolic process GO:0042572 IBA
    retinol metabolic process GO:0042572 IEA
    retinol metabolic process GO:0042572 ISO
    retinoic acid metabolic process GO:0042573 IBA
    retinoic acid metabolic process GO:0042573 IEA
    retinoic acid metabolic process GO:0042573 ISO
    response to ethanol GO:0045471 IEP
    behavioral response to ethanol GO:0048149 IEA
    behavioral response to ethanol GO:0048149 ISO
    response to steroid hormone GO:0048545 IEA
    response to steroid hormone GO:0048545 ISO
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    mitochondrion GO:0005739 IEA
    mitochondrion GO:0005739 ISO
    cytosol GO:0005829 IBA
    cytosol GO:0005829 ISO
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Adh1 in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Adh1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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