Gene description for Cadm2
Gene name cell adhesion molecule 2
Gene symbol Cadm2
Other names/aliases 2900078E11Rik
9330131D06
A830029E02Rik
Igdf4d
Igsf4d
NECL3
SynCAM 2
SynCAM2
Species Mus musculus
 Database cross references - Cadm2
ExoCarta ExoCarta_239857
Vesiclepedia VP_239857
Entrez Gene 239857
UniProt Q8BLQ9  
 Cadm2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cadm2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cell adhesion GO:0007155 IEA
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IBA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    axon GO:0030424 IEA
    axon GO:0030424 ISO
    neuronal cell body membrane GO:0032809 IBA
    neuronal cell body membrane GO:0032809 ISO
    synapse GO:0045202 IEA
 Experiment description of studies that identified Cadm2 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cadm2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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