Gene description for Dera
Gene name 2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
Gene symbol Dera
Other names/aliases 2010002D22Rik
2500002K03Rik
DEOC
Species Mus musculus
 Database cross references - Dera
ExoCarta ExoCarta_232449
Vesiclepedia VP_232449
Entrez Gene 232449
UniProt Q91YP3  
 Dera identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Dera
Molecular Function
    deoxyribose-phosphate aldolase activity GO:0004139 IBA
    deoxyribose-phosphate aldolase activity GO:0004139 IEA
    deoxyribose-phosphate aldolase activity GO:0004139 ISO
Biological Process
    deoxyribonucleotide catabolic process GO:0009264 IBA
    deoxyribonucleotide catabolic process GO:0009264 IEA
    carbohydrate catabolic process GO:0016052 IBA
    deoxyribonucleoside catabolic process GO:0046121 IEA
    deoxyribonucleoside catabolic process GO:0046121 ISO
    deoxyribose phosphate catabolic process GO:0046386 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Dera in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Dera
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Foxp3  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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